Scientifically it is stated that basic premise of the biological or physiological explanation for the occurrence of fear and anxiety is that problems with brain functioning lead to anxiety disorders. For example, current research indicates that generalized anxiety disorder is caused by excessive neurological activity in the area of the brain that is responsible for emotional arousal, and this increased level of arousal is experienced as anxiety.
So we can say that we try to imagine the worst and the horrible and the anticipation of such things leads to more anxiety.If we think carefully it can be said that the basis of fear lies mostly in our perspective and how our brain is programmed. Recently i was reading a book related to marketing and there the author mentions what ever action and decisions we take and do in our life is relate to genetic blue prints ie how we are taught to think about a particular issue by our parents.So the basis of assumptions rises from there. I have felt sometimes not thinking about a certain issue helps and at other approaching the matter from a different perspective talk to a friend or a near one(not a family member) they might have something else to offer.So next time something negative comes up in your mind stop for a while and think if its your genes which are shouting and making you anxious.
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